William Rowell

+1 510 764 3267



Fremont, CA
United States

wjrowell.info

william@wjrowell.info  Github /  Twitter

Employment

Senior Bioinformatics Scientist @ Pacific Biosciences

Menlo Park, California

Description: I work with customers and internal teams to develop new or improve existing applications and analysis workflows for single molecule, long-read sequencing. I help my associates in sales and marketing turn proof of principle or pilot experiments into equipment sales or marketing collateral.

Accomplishments: developed and improved upon workflows for variant calling and phasing of PacBio circular consensus sequence data • collaborated with wet lab scientists to improve targeted capture sequencing protocol • provided data analysis solutions and expertise for multiple targeted sequencing collaborations

Scientific Programmer @ Expression Analysis, Q2 Solutions

Morrisville, North Carolina

Description: I delivered high-quality next-generation sequencing data to our clients in a timely manner.

Accomplishments: with others in my team, guided the development of delivery and analysis pipeline enhancements • developed tools for tracking tasks and errors • data-driven process improvement • recognized for providing exceptional customer service

Research Specialist @ Howard Hughes Medical Institute, Janelia Research Campus

Ashburn, Virginia

Description: I supported the research of the project teams and labs at Janelia by providing consultation, conducting high-throughput animal behavior experiments, analyzing data, and writing software.

Accomplishments: acted as liaison and translator between different disciplines in large-scale scientific collaboration • screened over 2000 Drosophila melanogaster lines through high-throughput locomotor / optomotor / phototaxis assay • screened over 300 D. mel. lines through high-throughput olfactory assay • established guidelines for storing data and metadata • curated and analyzed data and metadata • aided in design of novel behavioral assays, including instrument design and testing, protocol refinement, and data analysis tools • wrote suite of tools for analysis of D. mel. activity / sleep data • wrote and maintained automated pipeline for fluorescence imagery analysis

Education

MA in Molecular and Cell Biology

University of California, Berkeley
Berkeley, California

Thesis: A genetic selection to identify regulatory elements driving the earliest zygotic transcription in Drosophila melanogaster.

BS Biology with Chemistry minor

University of North Carolina, Chapel Hill
Chapel Hill, North Carolina

Research: Using classical genetic techniques and molecular biology to dissect the genetics of the resistance of Arabidopsis thaliana to the fungal pathogen Peronospora parasitica.

Skills

Computational

shell scripting, HPC clusters & version control

Python, NumPy, pandas & Matplotlib

bioinformatic analysis with published tool

20 years of experience administering home Linux servers and workstations

Molecular biology and genetics

quality control, critical interpretation & troubleshooting problems with NGS data

nucleic acid isolation, manipulation, cloning & analysis

RNA in situ hybridization & visualization

bacterial genetics, fruit fly husbandry & classical eukaryotic genetics

Technical

adapting techniques, off-the-shelf products & custom hardware and software

experimental design & protocol refinement

equipment testing, calibration & maintenance

logistics for high-throughput operation

wide field microscopy & confocal fluorescence microscopy

image acquisition & analysis

Professional

proven track record in collaborative science

determined problem solver & data-driven process improvement

training researchers in biological techniques & laboratory management skills

training researchers in introductory programming & best practices

liaising and translating between research staff & operations staff

consulting for sales, project managers & clients

presenting data in written & oral formats

Initiatives

Volunteer Instructor, Software Carpentry

George Washington University, Ashburn, Virginia; HHMI, Janelia Research Campus, Ashburn, Virginia

Courses: Train researchers in core software skills to improve their efficacy, such as use of the Unix shell and Python for data analysis.

Instructor, Introduction to Python Programming

HHMI, Janelia Research Campus, Ashburn, Virginia

Courses: Organized, planned curriculum, wrote lessons, and led instruction for class tailored to the needs of JRC researchers.

Hobbies

camping, hiking, ultimate frisbee, travel, baking